Steer clear of concomitant use of tucatinib with CYP3A substrates, wherever negligible focus improvements might lead to critical or daily life-threatening toxicities. If unavoidable, lower CYP3A substrate dose As outlined by product or service labeling. grapefruit will boost the degree or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. https://davidm158ydg6.angelinsblog.com/profile