These results, along with a prior report demonstrating that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,two support the notion of focusing on ACKR3 as a unique way to modulate the opioid program, which could open up new therapeutic avenues for opioid-linked disorders. We independently investigation, evaluate, https://roberte905cvn2.wikiconversation.com/user