Last of all, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive method, which might decrease the dose of every ingredient by sixty% for postoperative analgesia. For those who get dizzy when standing: This situation known as orthostatic hypotension. Clonidine can make this situation worse. https://www.proleviate.com/post/the-new-pain-killer-conolidine