Bad/Intensive Metabolizers, CYP2D6 The formation with the Lively metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Approximately 7% from the inhabitants has minimized action of the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme program. These people are “weak metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among the other drugs. https://hippod297zgl1.blogmazing.com/profile